Amarantus Therapeutics has developed a robust discovery platform PhenoGuard Protein Discovery Engine that allows Amarantus scientists to rapidly discover novel secreted human proteins with biological activity for specific indications. Our Platform consists of our PhenoGuard Cell Line Library and highly sensitive Target Validation cell culture systems that provide accurate results and allow our scientists to make better go/no-go decisions. The first application of our Protein Discovery Engine was in the discovery of MANF from astrocytes.